$350m for @AdamWeWork. The world has not gone mad. Read why Marc Andreessen (@pmarca) did it. Plus @ReidHoffman on AI, Josh Nicholson on Science and AI, @BrianSolis on Web3 marketing @Alexoppenheimer on valuing companies, and much more. TOTW @matt_gray_

This week @bhorowitz and David Weiden of @KhoslaVentures talk about culture as a catalyst for a healthy company. @SamirKaji talks about the importance of emerging seed investors, and @HunterWalk discusses the importance of angels with operating experience to a CEO. @Om Malik and @BGurley talk about survival techniques during downturns. How is a Unicorn Born? That is the common theme.

This week I contrast the views of Substack co-founder Hamish McKenzie and Vox’s Peter Kafka. And I couldn’t resist a few suggestions to Hamish. The Future of the Newsletter is the future of the network, whatever the outcome, so this is important.

Deep in the heart of summer and @Om links to the 200 best dance songs of all time. I’m passing it on as a gift. And DeepMind figured out the structure of 200m human proteins. Now that really is a gift. Data and Science are crucial to humanity’s future. Deep Minds think alike is this week’s theme.

In a week where the public markets rebounded, private market talked was all about downside. Content from @ttunguz @jasonlk @geneteare and @crunchbase is startup of the week.

A @bgurley tweet pointed to an essay written by Isaac Saul (@Ike_Saul), founder of Tangle. His essay challenges the idea that misinformation is a problem. He argues that nothing we humans think we know is actually true. Rather it is our provisional understanding. Of course, he is right. Truth is overrated

So many points of view about the venture ecosystem. Some panic, some optimism, some ‘wait and see’. Modern media likes to take sides but all of these sentiments are appropriate because more than one thing is happening. All at the same time. And many of them are good.

An average sports stadium can hold 50-100,000 fans. But teams have millions and sometimes billions of fans. What is the rue value of rights to stream games? This week Amazon bought UK Champions League rights. Can we expect more money to come for sports rights and who should own them?

Netflix announced 300 layoffs and Brex pulled the rug on its small business customers. But LocalGlobe raised $500m, InFarm announced to new farms and eBay bought NFT firm KnownOrigin. Making the right choices will help us all to live long and prosper. Web 3 seems to still be a good choice.

The Dark Ages describes a time when little or nothing changed. There was no progress. It needed the agricultural and industrial revolutions to break out from the dark. 2022 might seem dark but there is innovation all around us. Adapt or Die is this week’s theme. And unlike the dark ages, adaptation is an option. Content from @bgurley @samirkaji @sethlevine @geneteare @sequoia